Acetyl chloride,2-cyano-
Acetyl chloride,2-cyano-
CAS: 16130-58-8
Molecular Formula: C3H2ClNO
Acetyl chloride,2-cyano- - Names and Identifiers
| Name | Acetyl chloride,2-cyano- |
| Synonyms | Cyanoacetyl chloride Acetylchloride, cyano- Acetyl chloride, cyano- Acetyl chloride,2-cyano- Cyanoacetic acid chloride |
| CAS | 16130-58-8 |
Acetyl chloride,2-cyano- - Physico-chemical Properties
| Molecular Formula | C3H2ClNO |
| Molar Mass | 103.50708 |
| Density | 1.2170 (rough estimate) |
| Boling Point | 73-75 °C |
| pKa | 0.26±0.10(Predicted) |
| Storage Condition | Room Temprature |
| Refractive Index | 1.4510 (estimate) |
| Use | Intermediate |
Acetyl chloride,2-cyano- - Upstream Downstream Industry
| Downstream Products | tert-Butyl cyanoacetate 2-cyano-N-[4-(trifluoromethyl)phenyl]acetamide |
Acetyl chloride,2-cyano- - Introduction
Gefitinib is an effective treatment for non-small cell lung cancer. Its structure contains an important intermediate called Acetyl chloride,2-cyano-(Gefitinib intermediate 3).
The properties of Acetyl chloride,2-cyano-mainly include physical properties and chemical properties. It is a white solid, sometimes yellow or yellow-brown, crystalline material. In terms of chemical properties, Acetyl chloride,2-cyano-has some important functional groups, such as ketone and allyl, which play a key role in the subsequent drug synthesis.
Acetyl chloride,2-cyano-is mainly used to synthesize Gefitinib, the non-small cell lung cancer treatment drug Gleevec (Gefitinib). Acetyl chloride,2-cyano-is an important intermediate product in the synthesis of gefitinib, which is finally obtained after a series of chemical transformations. Gefitinib is a tyrosine kinase inhibitor of epidermal growth factor receptor (EGFR), which can block the proliferation and metastasis of tumor cells by inhibiting the activity of EGFR kinase, so as to achieve the effect of treating lung cancer.
Acetyl chloride,2-cyano-is generally prepared by organic synthetic chemistry. The specific synthetic route is more complex, usually through multi-step reaction and separation and purification process to obtain high purity Acetyl chloride,2-cyano-.
For the safety information of Acetyl chloride,2-cyano-, the following points need to be paid attention. First of all, the synthesis process may involve organic solvents and organic reactants, the need to pay attention to the fire source and avoid inhalation, intake and skin contact. Secondly, intermediate 3 is a solid, in the operation need to pay attention to protect the hand to avoid direct contact. In addition, the specific use and storage conditions need to be determined according to the specific chemical properties and material safety data sheets to ensure safety and stability.
The properties of Acetyl chloride,2-cyano-mainly include physical properties and chemical properties. It is a white solid, sometimes yellow or yellow-brown, crystalline material. In terms of chemical properties, Acetyl chloride,2-cyano-has some important functional groups, such as ketone and allyl, which play a key role in the subsequent drug synthesis.
Acetyl chloride,2-cyano-is mainly used to synthesize Gefitinib, the non-small cell lung cancer treatment drug Gleevec (Gefitinib). Acetyl chloride,2-cyano-is an important intermediate product in the synthesis of gefitinib, which is finally obtained after a series of chemical transformations. Gefitinib is a tyrosine kinase inhibitor of epidermal growth factor receptor (EGFR), which can block the proliferation and metastasis of tumor cells by inhibiting the activity of EGFR kinase, so as to achieve the effect of treating lung cancer.
Acetyl chloride,2-cyano-is generally prepared by organic synthetic chemistry. The specific synthetic route is more complex, usually through multi-step reaction and separation and purification process to obtain high purity Acetyl chloride,2-cyano-.
For the safety information of Acetyl chloride,2-cyano-, the following points need to be paid attention. First of all, the synthesis process may involve organic solvents and organic reactants, the need to pay attention to the fire source and avoid inhalation, intake and skin contact. Secondly, intermediate 3 is a solid, in the operation need to pay attention to protect the hand to avoid direct contact. In addition, the specific use and storage conditions need to be determined according to the specific chemical properties and material safety data sheets to ensure safety and stability.
Last Update：2024-04-09 21:01:54
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Product Name: Acetyl chloride, cyano- Visit Supplier Webpage Request for quotation
CAS: 16130-58-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 16130-58-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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